1，宿主 Host: Escherichia coli (E. coli)
2，种类Species: Rat
3，蛋白类型Protein Type: Recombinant
4，别名Synonyms: IL-1, IL1F2, IL1-BETA, IL-1BETA, IL1beta, IL-1B, IL-1beta, Il-1b, IL1B, il1-b, zgc:111873
5，纯度Purity: 95% by SDS-PAGE
6, 应用范围Application: WB， Elisa， Functional Studies
7.背景Background:
IL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, B-cell maturation and proliferation, mitogenic FGF-like activity and stimulation of the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Recombinant rat IL-1beta is a 17.4 kDa protein containing 153 amino acid residues.
8保存和稳定性Storage&Stability:
Avoid repeated freeze and thaw cycle.Store at 2-8℃ for delivery and store at -20 or -70℃ for future use. The loss rate of the target protein which describes the stability was determined by accelerated thermal degradation test.That is to incubate the protein at 37℃ for 48h and no obvious degradation and precipitation were observed.The loss of this protein is less than 5% within the expiration date under appropriate storage condition.